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ADVANCED

 

CELL THERAPY
SOLUTIONS

Our expertise in biology, robotics, in silico analysis and
bioinformatics helps cell therapy pioneers advance the
discovery phase of their clinical candidates.
Advanced

SLIM DISPLAY FOR
CAR-T OPTIMISATION

OXGENE’s proprietary CAR-T / antibody discovery platform targets challenging membrane proteins for the development of your CAR-T and other biologics. Antibody humanisation, affinity maturation and complex gene editing complete our discovery workflow.

/oxgene/cell_therapy/slim_display_for_cart_discovery.aspx

Advanced

PLASMIDS AND
CELL LINES

Our optimised LentiVEX™ plasmid system delivers improved yield, quality and safety. Our cell line development services are underpinned by expertise in molecular biology and genetic engineering and supported by state of the art automation.

/oxgene/cell_therapy/plasmids_cell_lines.aspx

Advanced

TRANSIENT LV
PRODUCTION SYSTEMS

Our optimised third generation packaging plasmids and clonal HEK293 cell line provide enhanced safety and increased lentiviral yield. 

/oxgene/cell_therapy/transient_lv_production_systems.aspx

Advanced

PROMOTER DISCOVERY OPTIMAL EXPRESSION

We offer promoter discovery services for optimal on-target therapeutic gene expression. Our promoter discovery team will fine-tune the expression and localisation of your therapeutic transgene with benefits for viral vector utility, safety and efficacy, optimizing the performance of your novel therapeutic. 

/oxgene/cell_therapy/promoter_discovery.aspx

Advanced

LV PACKAGING AND PRODUCER CELL LINES

Stable clonal LentiVEX™ packaging and promoter cell lines offer easy scale up, reduced cost of goods and reduced process complexity. 

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OXGENE's advanced technology and service solutions
help pioneering companies accelerate the discovery
phase of breakthrough cell and gene therapies.

RYAN CAWOOD, CHIEF SCIENTIFIC OFFICER, OXGENE & WuXi ATU

 

OXGENE provides an integrated solution that
supports your entire discovery and validation workflow

GET IN TOUCH

 

Our Publications

JBC SLIM Paper
DDW SLIM Case Study
RMN Lentivirus Feature
GEN CRISPR Article

 

Are you ready for GMP Manufacture?

WuXi Advanced Therapies is a global Contract Testing, Development
and Manufacturing Organization (CTDMO) dedicated to accelerating
progress and time to market for cell and gene therapies.

GMP MANUFACTURE

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