ADVANCED Plasmids and Cell LinesTransient AAV ProductionTESSA: Scalable AAV Production GENE THERAPY SOLUTIONS Our proprietary gene therapy manufacturing solutions help pioneering companies achieve high-titre, scalable and cost-effective viral vector production, helping to accelerate clinical success. Advanced PLASMIDS AND CELL LINES Optimised XAAV™ plasmid system including reconfigured rep-cap and minimised Ad5 helper plasmids improve AAV yield and quality. Cell line development services are underpinned by expertise in molecular biology and genetic engineering and supported by state of the art automation. /oxgene/gene_therapy/plasmids_and_cell_lines.aspx Advanced TESSA: SCALABLE AAV PRODUCTION Our proprietary Tet-enabled self silencing adenoviral (TESSA™) AAV manufacturing system delivers gene therapy pioneers highyield, high quality AAV in a scalable, contaminant, chemical and transfection free process. /oxgene/gene_therapy/tessa_scalable_aav_production.aspx Coming soon PROMOTER DISCOVERY Proprietary bioinformatics aid the rational design of combinatorial promoter / enhancer libraries that we screen for optimal promoter combinations designed to your specifications. Link/Unlink This Text Here Advanced TRANSIENT AAV PRODUCTION Our industry leading technology platform provides flexible, high titre rAAV production. Our reconfigured Rep-Cap and modified Ad5 helper plasmids combined with a GMP banked clonal suspension HEK293 cell line offer gene therapy companies an improved AAV yield. /oxgene/gene_therapy/transient_aav_production.aspx/oxgene/gene_therapy/transient_aav_production.aspx Coming soon CAPSID DISCOVERY Proprietary bioinformatics and TESSA™ technology enable the generation of a genotype : phenotype linked AAV library we can screen for novel functional capsids with your desired infectivity and specificity. Link/Unlink This Text Here Our industry leading biomanufacturing solutions help pioneering companies scale up and advance clinical manufacture of their breakthrough cell and gene therapies RYAN CAWOOD, CHIEF SCIENTIFIC OFFICER, OXGENE & WuXi ATU Get the best results with comprehensive technical support from our expert scientists. TALK TO US ABOUT YOUR PROJECT Our Publications Are you ready for GMP Manufacture? WuXi Advanced Therapies is a global Contract Testing, Development and Manufacturing Organization (CTDMO) dedicated to accelerating progress and time to market for cell and gene therapies. GMP MANUFACTURE
