The manufacturing of viral vectors is a major bottleneck in delivering cell and gene therapies to the patient. Reducing the cost of goods while maintaining a high quality of the viral materials requires disruptive changes to the process. A novel approach to vector design through promoter and capsid engineering leads to more effective and specific vectors. Alternatives to the standard transfection-based process improve process efficiency through increased titres and reduced cost of goods. We will discuss challenges and trends within the cell and gene therapy industry, and how advances in technology help accelerate the development of breakthrough therapies.
GROUP LEADER OF PROCESS DEVELOPMENT, OXGENE
Jakub Krakowiak is the Group Leader of Process Development at OXGENE with a BSc in Biotechnology (University of Edinburgh), EngD in Biopharmaceutical process development (Newcastle University) and extensive experience in the viral vector production. At OXGENE, he developed and scaled up the process of production for LV, AAV and AdV vectors and continues to oversee further development of company’s processes and technologies.
You can register for this webinar here: https://webinars.endpts.com/addressing-cell-and-gene-therapy-challenges-through-advances-in-scientific-and-manufacturing-technology/