Characteristics and functionality of OXGENE’s suspension HEK293 cell line platform for viral vector manufacture - Vaccitech Collaboration
HEK293 cell lines have been utilised extensively in the production of AAV, Lentiviral and Adenoviral vectors for clinical applications. Suspension adapted variants, in contrast to adherent mode, represent a more attractive alternative, facilitating animal component-free, scalable, and highly flexible processes, along with increased compliance with cGMP manufacture. OXGENE has fully characterised a cGMP-banked HEK293 cell line, and has produced a range of engineered and application specific derivatives.
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