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03 March 2020

Pooled CRISPR screening

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OXGENE’s CRISPR pooled screening service

Genetic screens are powerful tools used to identify genes involved in diseases and identify new drug targets (1). CRISPR screens enable unbiased discovery of drug targets or study underlying causes of disease. OXGENE’s screening platform offers CRISPR-knockout (CRISPRko) and activation screens (CRISPRa) using sgRNA libraries against either the whole genome or specific gene families. In addition, we can also quickly and efficiently build custom-designed pooled sgRNA libraries and provide complete workflows for CRISPR pooled screens; from cell line selection and optimisation, through to bioinformatic analysis of the screening results.

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